Today's fascinating episode deals precisely with the great transformations in evolutionary history: land-dwelling animals evolving into whales and dolphins, fish into four-legged terrestrial creatures (tetrapods), and the Cambrian Explosion.
Many of the body parts of all animals are basically specialized adaptations of the same one basic general structure, and it turns out that they are each governed by a small set of powerful genes, which all modern animals seem to share. This explains, for instance, why there are some weird cases in which animals can grow body parts in the wrong places: legs out of their heads, antennae out of their torsos, extra ribs, etc., and why it is possible to use genes from one type of animal into another.
Among those interviewed are Neil Shubin, who recently published Your Inner Fish; Philip Gingerich, the man who discovered the evolutionary stages of whales; Sean Carroll, and more.
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